What effect does cortisone therapy have on the immune response?

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Cortisone therapy, a type of corticosteroid treatment, primarily suppresses the immune response. This suppression occurs because corticosteroids like cortisone work by inhibiting various components of the immune system, including the activation of T-cells and the production of certain cytokines that are crucial for immune function.

By dampening the immune response, cortisone can help reduce inflammation and treat autoimmune conditions where the body’s immune response is abnormally high. This effect is beneficial in managing symptoms of conditions such as rheumatoid arthritis, asthma, or allergies, where inflammation is a significant concern. However, this suppression can lead to an increased risk of infections, as the body’s defense against pathogens is compromised.

In contrast, the other choices do not accurately reflect the primary effects of cortisone therapy: it does not enhance the immune response or stimulate bacterial growth, nor is its primary role to inhibit inflammation alone, as inflammation control comes as a consequence of immune suppression. Therefore, understanding cortisone therapy through the lens of immune modulation highlights its significant role in clinical practice.

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