What is the condition where insulin is not adequately secreted, or tissues are resistant to its effects called?

Diabetes Mellitus is the condition characterized by inadequate insulin secretion, tissue resistance to insulin, or both. In this condition, the body's ability to regulate blood glucose levels is impaired, leading to hyperglycemia, which can cause various complications if left unmanaged.

The condition encompasses different types, primarily Type 1 Diabetes Mellitus, where there is a lack of insulin production due to autoimmune destruction of pancreatic beta cells, and Type 2 Diabetes Mellitus, characterized by insulin resistance in tissues and often accompanied by insufficient insulin secretion over time. Recognizing this condition is vital for effective management and prevention of complications such as cardiovascular disease, neuropathy, and kidney failure, among others.

The other options listed do not pertain to issues of insulin secretion or action. Malaise refers to a general feeling of discomfort or unease, tachycardia signifies an increased heart rate which can be due to various reasons, and emesis refers to vomiting, which is also unrelated to the process of glucose metabolism and insulin function.