What is the onset time for Humulin 70/30 and Novolin 70/30 mixed insulin?

The onset time for Humulin 70/30 and Novolin 70/30 mixed insulin is accurately described as 30-60 minutes followed by a peak effect that occurs between 1-2 hours after administration. This combination insulin contains 70% NPH (isophane insulin) and 30% regular insulin. The regular insulin component typically has a fast onset, which is roughly 30 minutes, while the NPH component takes longer to start exerting its effects due to its more gradual release into the bloodstream.

The mixed formulation allows for a dual action; the regular insulin provides a quick control of blood glucose levels shortly after injection, while the NPH portion sustains the blood sugar control over a longer duration. Understanding the timing of onset is crucial for managing blood glucose levels effectively, particularly in relation to mealtimes.

In the context of treatment and patient education, knowing this onset can help individuals administering the insulin to plan for meals and monitor for potential hypoglycemia if the onset is too close to a meal consumption.