What is the peak action time for intermediate insulin like NPH?

The peak action time for intermediate insulin, such as NPH, is indeed 4 to 12 hours after administration. This characteristic is important for understanding how to manage blood glucose levels in patients requiring insulin therapy.

NPH insulin is designed to provide a more prolonged effect compared to rapid-acting insulins, which typically start to work within 15 minutes and peak around 1 to 2 hours. With NPH, the delayed onset and extended peak action allow for better glycemic control throughout the day, especially when used in conjunction with short-acting insulins. The peak period ensures that the insulin works effectively to lower blood sugar levels, particularly after meals.

Understanding the peak action time helps healthcare providers determine the best times to administer NPH in relation to food intake and other insulin preparations. This knowledge is crucial for preventing episodes of hypoglycemia and managing diabetes effectively.