Which of the following is classified as an intermediate insulin drug?

NPH (Humulin N, Novolin N) is classified as an intermediate-acting insulin because it has a slower onset and a longer duration of action compared to rapid-acting insulins. Intermediate insulin typically takes around 1 to 2 hours to begin working, with a peak effect between 4 to 12 hours and lasting up to 24 hours. This makes it suitable for patients needing insulin coverage for a longer period, particularly between meals and overnight.

In contrast, the other options listed are rapid-acting insulin (Lispro and Insulin Glulisine) or long-acting insulin (Lantus). Rapid-acting insulins start working within minutes and are used primarily for controlling blood sugar during meals, whereas long-acting insulins provide a steady level of insulin over an extended period, typically lasting up to 24 hours without a pronounced peak. Understanding these classifications is essential for managing diabetic patients effectively, as it informs the timing and dosage of insulin administration.